Stereology Analyzer enables the user to optionally define one or more ROIs and a grid that overlays the ROIs or the whole image. Stereology Analyzer implements long-standing and accepted stereology techniques that employ an interactive grid overlaid on regions of interest (“ROI”) in a 2D image. Note that standard 2D image processing techniques will hardly provide 3D information from sections, except for the volume fraction value. By definition, stereology is the science that studies the geometric relationship between a structure that exists in 3D space and a set of images of the same structure that are fundamentally defined in 2D space (images of slices, sections, or projections). The term stereology was first introduced in 1961 when the International Society for Stereology (ISS) was founded by a small group of scientists, although the basis of stereology theory was defined more than 300 years ago. Stereology Analyzer graphical user interface Stereology Background
#Stereology tutoral software#
Stereology Analyzer is a faithful implementation of long-accepted stereological and statistical methods in the context of today’s software technology. In fact, stereology is also frequently used to validate the proper performance of complex, automated algorithms. Where automated processes don’t exist or fail to compute SOI parameters reliably, stereology is the method of choice to estimate these parameters. The common factors in these fields are the need to characterize and quantify microscopic structures of interest (“SOI”) and the use of very large images (i.e., virtual slides or composite images). This tool is general in its implementation, but has applicability to various scientific domains, most commonly in medicine, materials science, and geology. Stereology Analyzer is a simple to use software tool for reliably estimating quantifications of important 3D structures. Stereological analysis of 3D structures using 2D section or projection images
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